NFL Week 3 Picks and Predictions: 49ers vs. Giants

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San Francisco 49ers Aim for Rare 3-0 Start with Thursday Night Win Against the New York Giants

The San Francisco 49ers are looking to continue their early-season success as they aim for just their second 3-0 start in 25 years. The storied franchise last achieved this feat in 2019 and now has the opportunity to replicate it with a win against the New York Giants on Thursday night.

The Giants will face a tough challenge without star running back Saquon Barkley, who is currently recovering from an ankle injury. However, New York displayed resilience in their previous game, rallying from a 21-point deficit to secure their first win of the season against the Arizona Cardinals.

USA TODAY Sports will provide live coverage of the game, offering in-depth analysis and updates on all the action. Fans can stay tuned for more information and insights as the game unfolds.

In terms of player performance, the Giants’ tight end Darren Waller was expected to play a significant role in Thursday night’s game. However, he had zero catches and no targets late in the second quarter. Meanwhile, the 49ers converted three vital third downs and capitalized with a touchdown, showcasing their offensive prowess.

The Giants’ offensive line struggled to contain the 49ers, resulting in a near safety when Nick Bosa sacked Giants quarterback Daniel Jones near the goal line. Despite the Giants matching San Francisco’s opening drive field goal, the 49ers have displayed dominance with their explosive playmakers and stout defense.

Looking ahead to the game, the 49ers are favored by 10.5 points according to BetMGM. All eight of USA TODAY Sports’ NFL experts have chosen the 49ers as the winner, with five of them even considering it the lock of the week.

Sports betting enthusiasts have also shown faith in the 49ers, with quarterback Brock Purdy having one of the best odds for NFL MVP in his second professional season. Additionally, the 49ers boast some of the best early Super Bowl betting odds.

As fans eagerly anticipate Week 3 of the 2023 NFL season, the panel of NFL experts offers their predictions and analysis on the various undefeated and winless teams. With nine teams currently sporting a 2-0 record, the San Francisco 49ers stand out as a legitimate contender.

Football enthusiasts can also find valuable fantasy football rankings for Week 3, taking into account the point-per-reception scoring system used in most formats.

Ultimately, the San Francisco 49ers’ quest for a rare 3-0 start will be put to the test against the New York Giants on Thursday night. With their explosive playmakers and dominant defense, the 49ers are poised to continue their early-season success and potentially solidify their status as one of the top teams in the NFC.

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