The No. 4 Ole Miss Rebels travel to face the No. 21 Florida Gators on Saturday, September 26, 2026, at Ben Hill Griffin Stadium in Gainesville, highlighting a weekend of college football matchups.
College football’s Week 4 slate brings a collision of high-powered offenses, suffocating defenses, and early-season conference tests. From a high-profile showdown in Gainesville to defensive battles in the Big Ten and SEC, bettors and fans are weighing elite line-of-scrimmage play against explosive passing attacks.
Ole Miss and Florida Clash in Gainesville
Ole Miss Rebels and Florida Gators
The No. 4 Ole Miss Rebels carry an unblemished record into their road matchup against the No. 21 Florida Gators at Ben Hill Griffin Stadium, scheduled for Saturday, September 26, 2026, at 3:30 p.m. ET. Both teams enter at 3-0, with Florida sitting as a 3.5-point favorite. The Gators are coming off a 44-39 win at Auburn, while Ole Miss secured a 32-24 victory against LSU. Florida has won with high-end efficiency, averaging 54 points per game and 7.8 yards per play, which ranks fourth highest in the nation, alongside 21 touchdowns that place fifth nationally.
Florida’s offense has thrived under Philo, who has completed 47 of 64 passes for 721 yards with six touchdowns against two interceptions at a completion rate near 73 percent. Meanwhile, Baugh has emerged as a dominant force, rushing 54 times for 458 yards—ranking second in the FBS—and leading the nation with eight touchdowns at an 8.5-yard clip. Baugh gashed Auburn for 162 yards and three scores on 26 carries, including 106 yards and two scores after halftime, adding to a season tape that already features a 75-yard touchdown run. In the 44-39 triumph that vaulted the Gators to a 3-0 start for the first time since 2019, Philo logged 202 passing yards and one touchdown while the ground game shouldered the workload, proving he did not need massive numbers to defeat Auburn.

Thomas Casale, via Yahoo
For Ole Miss, quarterback Chambliss anchors a pass-heavy attack averaging 330.7 passing yards per game on the road, while Florida allows 94.7 rushing yards per game and 21 points per game. Chambliss has completed 77 of 110 passes for 924 yards with seven touchdowns and two interceptions. During the 32-24 victory over LSU, he put forth his finest showing by completing 33 of 48 passes for 363 yards, generating three touchdowns and scrambling 14 yards for the score that permanently gave Ole Miss the lead. That display stretched his streak of consecutive games with a touchdown pass to 16, putting him level with Eli Manning for the third-most in program history.
Big Ten Defensive Grinds and Market Totals
Big Ten Defensive Grinds and Market Totals
In the Big Ten, No. 17 Iowa meets No. 18 Michigan with a low opening total that has drawn sharp betting interest at sportsbooks. Allowing a mere 4.3 points and 176.7 yards per contest, the Hawkeyes pace the nation in scoring defense, whereas Michigan places inside the top 10 countrywide for total defense, passing defense, tackles for loss, and sacks. Yet the Hawkeyes are also quietly averaging 268 rushing yards per game with an offensive line that has allowed only one sack, clearing 500 total yards twice in their first three outings, including 640 yards and 32 first downs against Northern Iowa without leading backs Kamari Moulton and L.J. Phillips, both of whom Kirk Ferentz sounded optimistic about getting back.
Michigan counters with quarterback Bryce Underwood, who has thrown for 504 yards and added 156 rushing yards, alongside wide receiver J.J. Buchanan averaging 17.7 yards per catch. When going up against a top-tier home defense that has yet to encounter an attack matching Michigan’s size and athleticism, experts point out that a signal-caller capable of turning broken third downs into gains of 20 yards completely alters the equation against a low over/under line.
Georgia and Oklahoma Meet in SEC Play
Georgia and Oklahoma Meet in SEC Play
No. 2 Georgia hosts Oklahoma with the Bulldogs laying 14 points in a matchup carrying a 44.5 total. Oklahoma boasts the nation’s fourth-best scoring defense, holding opponents to 7.7 points per game after recently holding New Mexico to 185 yards in a 14-6 win. Spearheading the Sooners’ attack is quarterback John Mateer—who has accumulated 652 passing yards and six touchdowns—alongside dynamic weapon Isaiah Sategna III, whose resume already features a 53-yard scoring reception, a 34-yard receiving touchdown, and an 88-yard punt-return score.
Georgia’s offense has posted massive numbers through three weeks, scoring 63, 70, and 45 points, though they were ahead 38-3 at Arkansas before giving up two late touchdown drives. Quarterback Gunner Stockton has been efficient, running back Nate Frazier was listed as day-to-day by head coach Kirby Smart, and the Bulldogs have allowed 13.3 points per game while giving up no points in the first or third quarter all season. As conference play heats up, these intersecting offensive explosions and defensive walls will set the hierarchy for the rest of the autumn.