2023-10-20 08:55:39
Increases of at least 5 body mass index units double the risk, which remains even after further weight loss.
A study carried out on more than 43,000 people, monitored for more than 15 years, indicates that body weight gain over a period of 5 years increases the risk of atrial fibrillation (AF). Compared to people who maintained their weight, those who experienced increases of between 2.5 and 5 body mass index (BMI) units saw their risk increase by 24%. This reached 95% with increases of 5 or more BMI units. In contrast, losing the same number of BMI units did not result in any risk modification.
Tanja Charlotte Frederiksen, a researcher at the Department of Cardiology at Aarhus University and director of the study, states that previous studies aimed at elucidating this association have yielded contradictory results. Although bariatric surgery and the use of semaglutide have shown benefit in preventing AF, a study in patients with obesity or overweight and AF treated with catheter ablation failed in its primary objective, which was to reduce the rate of AF recurrence. through lifestyle interventions, including weight reduction. The association found in the current study remained consistent between the sexes, as well as in patients who were underweight at the beginning of the study, says Frederiksen. Taken together, the findings are consistent with those of a previous randomized trial, in which reducing overweight in patients who already had AF resulted in a decrease in symptoms and disease burden. M.T.T. (SyM)
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