2023-07-14 19:10:26
Title: Paracetamol: Studies Reveal Potential Psychological Side Effects of Common Painkiller
Date: 07/14/2023
Author: Sophia Lother
Many people use paracetamol – but is it harmless? Studies show that the painkiller can affect character.
Paracetamol is one of the most commonly used painkillers in Germany. According to a recent survey conducted by the consumption and media analysis (VuMA), 17 percent of the more than 23,000 respondents stated that they had taken paracetamol within the past 12 months. The painkiller is readily available without a prescription in any pharmacy, making it an easily accessible option for pain or fever relief. However, an increasing number of studies indicate that paracetamol could have significant effects on the psyche.
Paracetamol works differently in the body compared to ibuprofen, as it does not directly target inflammation but instead affects the central nervous system. Although the exact mechanism of action is yet to be fully understood, experts believe that the drug influences specific tissue hormones responsible for causing warning symptoms like pain. By interfering with the synthesis of these hormones, paracetamol reduces pain. However, it is crucial to pay close attention to the dosage, as listed by gesundheitsinformation.de portal:
– Paracetamol: 1000 mg/4000 mg
– Ibuprofen: 400 mg/1200 mg
– ASA: 1000 mg/3000 mg up to 65 years, 2000 mg from 65 years
While the well-known side effects of paracetamol, such as liver and gallbladder diseases, skin diseases, and immune system disorders (allergic reactions and airway narrowing), are listed on the package insert, further studies highlight additional implications. A long-term study conducted in the US with over 55,000 participants concluded that paracetamol could potentially damage hearing, particularly when taken more than twice a week.
Due to its inclusion in various combination preparations, accidental overdose of paracetamol presents a health hazard. People may unknowingly consume multiple medications containing paracetamol, especially in the case of children’s medicines, which are available in different forms. Although paracetamol is generally considered safe, even in high doses, it is by no means harmless.
Paracetamol poisoning typically manifests itself in four stages. Stage 1, which occurs a few hours after ingestion, may include vomiting, although some individuals may not exhibit any symptoms. Stage 2 (24 to 72 hours) can involve vomiting, nausea, abdominal pain, and abnormal liver function. Stage 3 (3 to 4 days) may include aggravated vomiting, jaundice, bleeding, kidney failure, and inflamed pancreas, while Stage 4 (after 5 days) can lead to either recovery or multiple organ failure, which can be fatal.
In addition to physical side effects, an increasing number of studies suggest that paracetamol use can have psychological implications. Researchers from Ohio State University found that paracetamol not only dulls pain but also dampens feelings. Emotional evaluations of participants who had taken paracetamol were significantly lower compared to those in the placebo group when presented with emotionally charged images. Another study conducted by the university revealed that individuals who took paracetamol were more willing to take risks, perceiving certain activities like bungee jumping or walking alone in unsafe areas at night as less risky. This behavior may be attributed to the painkiller’s ability to reduce negative emotions. The authors of the study emphasized the potential negative consequences of such risk-taking behavior.
Paracetamol is a drug recommended by the Center for Disease Control and Prevention for the treatment of mild COVID-19 infections. However, study co-author Baldwin Way suggests that individuals with mild COVID-19 symptoms who take acetaminophen (paracetamol) might be more inclined to engage in social activities, as they perceive the risk to be low. The influence of paracetamol on the COVID-19 vaccination is still under research.
It is important to note that the information provided in this article is not a substitute for professional medical advice. Consulting a doctor is crucial for the right diagnosis and appropriate therapy. Individuals should always discuss the intake of medications or dietary supplements with a doctor beforehand.]
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