A team of scientists from Instituto Sloan Kettering of New York has found that the way of signaling cell phone STING can become an item clave to prevent cells carcinogenic latents develop their progress until generating tumors aggressive after escaping from a tumor primary.
This research, published in the journal ‘Nature‘, states that drugs that activate the STING protein would help stop the extension of cancer on new places of the organism, a process known as metastasis. This is the main cause of the occurrence of deaths in the cancer patientswell the cancer cells are created in the tumor original and end up spreading to other organs and tissues in the body. STING may now be, according to these scientists, a way of escape so that those cells that are hidden can transform into an aggressive cancer months or even years after of having suffered a primary tumor.
“Most cancer deaths are due to metastasis”
John Massagué“Anything we can do to prevent these cells from waking up again or to help the immune system kill them could be of great benefit to many people,” said lead author of the scientific research and director of the Sloan Kettering Institute. according to the media ‘La Voz de Galicia’. Thus, the study has now found a key element in stopping metastasis with STING signalling, something that has never been identified before by science and has now been discovered after having verified it in a model of lung cancer in mice.
Massagué acknowledges that “the majority of deaths from cancer are due to metastasis”, so one of the possibilities for eliminate this process would be with the use of STING that would kill off malignant cells even before metastasis begins or try to keep cells forever in a latency.