Al Buffet Almodóvar & Jara We have received a case, which we have accepted, of a postmenopausal woman who did not need treatment or follow-up for osteoporosis but what did it take Prolia and now takes heavy damage. Warning: Prolia is a bone-breaking bone treatment.
the drug Prolia (denosumab) is a prescription medication to treat osteoporosis and reduce the risk of fractures in postmenopausal patients at high risk of bone fractures. Like any medication, Prolia can have side effects and risks associated with its use. Some of the possible side effects include:
- Pain in the muscles, bones and joints and in the head
- Rashes
- upper respiratory tract infections
- urinary tract infections
- Pain in the arms and legs
Besides, Prolia can increase the risk of atypical fractures of the femurespecially in patients who take the drug for a long time.
There have also been reported cases of osteonecrosis of the jaw in patients taking Prolia.
Al Buffet Almodóvar & Jara We have received a case, which we have accepted, of a postmenopausal woman who did not need treatment or follow-up for osteoporosis but who took Prolia and now takes heavy damage.
He started feeling pain in his extremities, then a fracture after a fall. That is when they prescribe the drug. During the five years that she is undergoing treatment for denosumab it improves a lot and even in the year 2022 they tell him that he is very well thanks to the medicine and that it has filled in all the gaps in the osteoporosis in the vertebrae.
In March 2022, his GP decided to suspend his treatment “because of how well he is doing” according to the x-rays. But… it began to get worse in September of that year, having to stop working and lead a normal life.
His ordeal in the ER began with unspecified severe back pain; lumbago with vertebral fractures; severe osteoporosis with multiple vertebral fracturesetc.
They send him a corset to immobilize his back and absolute rest for the nine broken vertebrae. Currently, cannot stand for more than 15 minutes without having to rest.
The last straw of a medicine is that its side effects are to increase an already existing problem that we are trying to get out of.
It’s what the drug does Prolia, break the bones.
The matter is very worrying because, as the experts comment, there is enough data to conclude that the withdrawal of the drug produces a negative rebound effect.
Withdrawal of the drug produces a rebound effect negative
The first to warn of the risk, at the end of 2016, was the Swiss Medicines Agency who warned that until February 2018 more than 110 notifications of multiple spontaneous vertebral fractures after denosumab withdrawal.
But others were known before problems of entity.
The Spanish Agency for Medicines and Health Products (AEMPS) had published a note in September 2014 warning that medicines containing denosumab as the active ingredient, such as Prolia or Xgeva, offer risk of osteonecrosis of the jaw and hypocalcemia.
How many damaged women can we be dealing with? The pharmacist who markets the drug, Amgenplaces the figure at 3.4% of the consumers who, after injecting the medication, suffer broken bones.
but there is studies that conclude that between 26 and 27% of patients who discontinued their treatment with denosumab suffered new fractures vertebral.
we in the Buffet Almodóvar & Jara We are legally analyzing the case to settle the possible responsibilities of the laboratory, the doctors and the Health Administration.