2024-05-21 17:46:32
Docs from the Syrian capital, Damascus, introduced that that they had detected a case of a really uncommon illness on the planet, which was found in a Syrian lady in her twenties.
The administration of Al-Mujtahid Hospital in Damascus introduced the registration of a uncommon illness (phagocyte activation syndrome), which was identified and handled, confirming that it’s the fourth case of its sort on the planet.
Director of Al-Mujtahid Hospital, Ahmed Abbas, stated {that a} medical crew from the Division of Joint Ailments and Rheumatology was in a position to deal with a uncommon case of a 26-year-old affected person who visited the hospital after being identified with Nonetheless’s illness, which is among the uncommon sorts of arthritis.
The contaminated lady confirmed signs of peak fever reaching 40 levels Celsius lasting for greater than every week, a attribute, non-pruritic pores and skin rash, persistent arthritis for greater than two weeks, and pharyngeal ache with supporting secondary standards together with lymphadenopathy, excessive liver yeast values, and unfavorable ANA and Rf assessments. Based on what was reported by the “Athar Press” web site, which is near the Syrian regime.
Based on Abbas, the analysis and therapy of the situation lasted roughly 8 months, stressing that early analysis contributed to saving the affected person’s life, as a result of the sort of illness results in immunodeficiency and extreme infections that result in demise.
He defined that phagocyte activation syndrome is “a severe, life-threatening systemic complication that may happen for a lot of causes, together with inflammatory and autoimmune illnesses, particularly in sufferers with Nonetheless’s illness. It’s an uncontrolled proliferation and activation of phagocytes that results in a cytokine storm and a number of organ failure.”
Based on a neighborhood newspaper, the Rheumatology and Immunology Marketing consultant and Head of the Musculoskeletal Ailments Division, Dr. Widad Aji, defined that throughout the affected person’s go to to the Joints Division, it was discovered that she had non-palpable purpura spreading over the decrease extremities and the decrease stomach with bleeding and mucus shedding, with a persistent fever of 39 levels and gentle hepatomegaly. , enlarged lymph nodes and laboratory assessments doc the analysis of phagocyte activation syndrome. A growth was famous within the affected person’s situation after a single dose of methotrexate, signs that describe phagocyte activation syndrome.
She identified that the affected person was positioned on methotrexate therapy at a dose of 4 drugs per week, and thru therapy, the medical crew started to handle, deal with, and comply with her rigorously, starting with aggressive therapy with steroids, till indicators of enchancment started to appear after which continued with immunotherapy till the illness has been in remission for greater than a yr till now.
Dr. Aji famous that phagocyte activation syndrome is a severe, life-threatening systemic complication that may happen for a lot of causes, together with inflammatory and autoimmune illnesses, particularly in sufferers with Nonetheless’s illness, which is an uncontrolled proliferation and activation of phagocytes that results in a cytokine storm and a number of organ failure.
She added that on this case, and based mostly on the significance of constant schooling, the function of methotrexate in a single dose as a attainable stimulating issue for phagocyte activation syndrome was mentioned, and its involvement in inflicting it was talked about in 3 instances within the medical literature, with this case being 4 globally.
Final up to date: Could 16, 2024 – 21:20
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2024-05-21 17:46:32