the potential of nanocarriers highlighted by messenger RNA vaccines

by time news

This technology used on millions of people is the result of many years of research. 330805280/AlexQ – stock.adobe.com

DECRYPTION – These tiny droplets of fat mimic the membranes of our cells. They allow the messenger RNA molecule to penetrate there, which it could not do alone.

All the credit for the success of Sars-CoV-2 vaccines does not go to messenger RNA alone. It also owes a lot to its carrier. “Without the lipid nanoparticles in which the messenger RNA was encapsulated, nothing would have been possible”explains the Pr Patrick Couvreur, professor of pharmacy at the University of Paris-Saclay, member of the Academy of Pharmacy.

Indeed, these tiny droplets of fat that mimic the membranes of our cells allow the messenger RNA molecule to penetrate them, which it could not do on its own. “They also protect the messenger RNA which is rapidly degraded in the body”specifies the Pr Elias Fattal, professor of galenic at the University of Paris-Saclay, and who directed the Institut Galien Paris-Saclay, a joint research unit dealing with the design of nanomedicines.

This technology used on millions of people is the result of many years of research. Nanoparticles are indeed a mode…

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