2023-07-28 11:24:36
New Research Reveals Importance of Zinc for Cell Division
A groundbreaking study published in the specialist journal “Cell Reports” has shed light on the crucial role of the micronutrient zinc in the process of cell multiplication. The research, conducted by a team from the University of Colorado, utilized specially developed sensors that change color upon binding to zinc.
Zinc is known to be essential for various bodily functions, including cell growth, DNA formation, immune system support, and protein component synthesis. Despite its significance, scientists have long remained uncertain about its precise mechanism of action.
By employing the innovative zinc sensors, the research team has discovered that improper zinc levels can disrupt cell reproduction. Too high or too low concentrations of zinc can cause cells to cease dividing. Additionally, the researchers made an intriguing observation termed the “zinc pulse.” Following cell division, there is a temporary surge in zinc levels, which subsequently decline after approximately an hour.
Professor Amy Palmer, one of the lead authors of the study, emphasized the significance of the breakthrough, stating, “These fluorescence sensors were a major breakthrough because they allowed us to measure zinc in single cells over many hours. We can watch how the cell prepares for division, how it divides, and how the two daughter cells go through the same process.” Notably, the sensors do not disrupt the normal cell processes, enabling accurate analysis.
Furthermore, this new technology opens up avenues for studying other effects of zinc in greater detail. Approximately 17 percent of the global population suffers from zinc deficiency, which can have severe consequences such as stunted growth and development in children, compromised immune function, and impaired wound healing. The research team posits that the zinc pulse might play a role in these conditions, as cell division cannot occur without it. “We don’t yet understand the exact reasons behind this phenomenon, but we suspect that the two new daughter cells require ample zinc for growth. Without the zinc pulse, they are unable to progress and must pause,” explained Palmer.
This ground-breaking research paves the way for future investigations into the intricate workings of zinc and its effects. Understanding the importance of zinc in cell division and its potential implications for various health conditions holds great promise for improving human well-being.
For further details, the research can be found in the journal “Cell Reports” under DOI 10.1016/j.celrep.2023.112656.]
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