2023-07-28 18:06:15
British scientists have created flies in the laboratory capable of reproducing by parthenogenesis, that is, without mating or artificial insemination, according to a study published today in the scientific journal Current Biology.
Some species of animals reproduce by parthenogenesis, but not mammals. Such reproduction has been observed in birds or reptiles – an example is the Komodo dragon, the world’s largest lizard. But it is the first time that such a thing has been achieved by genetically modifying animals in the laboratory.
The researchers, led by biologist Alexis Sperling of the University of Cambridge, first analyzed the genomes of two different varieties of the same species of fly, Drosophila mercatorum. The first of these varieties reproduces without fertilization, while the second does not. By identifying the differences in their genomes, they came up with some hypotheses about the genes involved in the process of parthenogenesis.
Based on these hypotheses, the researchers modified the genes of another species of fly, Drosophila melanogaster, which reproduces exclusively by mating a female with a male. It took six years and 220,000 flies, but they finally “built” Drosophila melanogaster flies in the lab that reproduce by parthenogenesis.
Although they have this ability, the genetically engineered flies don’t seem eager to use it: if there’s a male fly nearby, the females always turn to classical mating to produce offspring. As for those that were never found near the other leaf, only 1-2% eventually reproduced by parthenogenesis. This happens when they are about 40 days old, which is about halfway through their life.
Female flies born by parthenogenesis were found to sometimes also be able to reproduce without contact.
Note that all “babies” born by parthenogenesis, whether flies or other animals, are always female.
Source: RES-MPE
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