2023-04-27 21:38:12
He pancreatic cancer is one of the most aggressive that exists because by confusing its symptoms with other health problemsIt is usually detected in advanced stages. Although the investigations to treat it are continuous, recently a protein that causes pancreatic cancer.
How deadly is pancreatic cancer?
He cancer is one of the main causes of mortality Worldwide. According to information from the Pan American Health Organization (PAHO), he pancreatic cancer is one of the four types of cancer with the highest mortality rates, in men it represents 7.0 percent, while in women it is 7.2 percent.
In recent years, great advances have been made to treat the pancreatic cancerRecently, a small device was developed that delivers medication directly into the pancreatic tumor to reduce its size, on the other hand, a molecule was discovered that attacks cancer cells.
They discover a protein that causes pancreatic cancer: a hope to detect it in time/ Photo: iStock
Although these discoveries are important in the fight against pancreatic cancer, the truth is that no definitive cure has been found. However, one of the most important pieces of research to date could change the way the brains develop. pancreatic tumors.
A team of researchers from the Cold Spring Harbor Laboratory (CSHL) in New York, United States, made a discovery that could bring us closer to the timely diagnosis of pancreatic cancer, since they located a protein that accelerates the formation of pancreatic tumors.
What protein causes pancreatic cancer?
According to the results of the research, published in the popular science magazine Cancer Discovery, when exploring the RNA splicinga genetic process that occurs prior to the production of proteins found in the pancreatic tumors, a protein called SRSF1 was identified that is capable of causing pancreatitis, favoring the development of tumors.
They discover a protein that causes pancreatic cancer: a hope to detect it in time/ Photo: iStock
“Cells have various processes to keep SRSF1 levels constant, but cancer tends to find a way to overcome these checks and balances,” explains CSHL investigator Adrian Krainer.
The researchers explain that genes, RNA, and proteins work together with cells to keep cells stable. SRSF1 levels. However, the process can be interrupted by multiple factors, triggering inflammation in the pancreas and accelerating the formation of cancer cells.
To reach this conclusion, the researchers observed high levels of SRSF1 in the growth of pancreatic ductal adenocarcinoma (PDAC) in mice and organoids. When the SRSF1 levels stabilized, the organoids stopped growing, therefore, this discovery could be key to developing new treatments against pancreatic cancer to eradicate it in time.
They discover a protein that causes pancreatic cancer: a hope to detect it in time/ Photo: iStock
What can cause cancer in the pancreas?
Although the exact cause of the pancreatic cancerit is known that cancer originates when the tissue cells or organs grow uncontrollably to form tumors what can they be benign or malignant.
There are some factors that can increase the risk of developing this type of cancerfor example, the inflammation in the pancreas or pancreatitis, obesity, diabetes, smoking, or a family history of genetic syndromes.
Although this finding is encouraging, the researchers caution that more research is still needed to understand the genetic mechanisms of pancreatic cancer and, in this way, provide actionable information for the creation of effective treatments against pancreatic cancer.
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