2024-06-10 17:28:36
Analysis outcomes have proven that Viagra (ingredient identify: sildenafil), well-known as a remedy for erectile dysfunction, helps stop cerebrovascular dementia.
On the seventh (native time), a joint analysis workforce together with the College of Oxford within the UK investigated the results of ‘sildenafil’, the primary ingredient in Viagra, on cerebral blood vessels in 75 aged adults who had skilled micro-cerebral infarction and introduced these outcomes.
Researchers randomly assigned individuals to take Viagra, cilostazol, or placebo for 3 weeks. Contributors already had gentle to reasonable cerebrovascular illness earlier than the beginning of the examine. In the meantime, cilostazol is an antiplatelet drug that inhibits the formation of blood clots and is used to stop recurrence in sufferers who’ve skilled cerebral infarction.
This examine used the outcomes of cardiovascular physiology assessments, ultrasound, and purposeful MRI scans to judge the effectiveness of the drug.
Analysis outcomes confirmed that sildenafil improved cerebrovascular perform in high-risk teams for cerebrovascular dementia. Each sildenafil and cilostazol lowered vascular resistance within the mind, however sildenafil additional elevated blood circulate in cerebral blood vessels. As cerebrovascular resistance decreases and blood circulate will increase, blood can circulate extra easily to the mind. This prevents cerebrovascular dementia, which happens when blood circulate to the mind decreases. As well as, sildenafil had fewer negative effects resembling diarrhea in comparison with cilostazol.
Professor Alastair Webb, from the Wolfson Heart for Stroke and Dementia Prevention on the College of Oxford, stated: “That is the primary trial to point out that sildenafil enters the mind blood vessels and improves blood circulate in individuals with this illness.”
“Cerebral blood vessel injury can lead not solely to vascular dementia but in addition to stroke and cerebral hemorrhage, so warning is required,” he stated. “If Viagra, a extensively commercialized remedy, can be utilized to stop dementia, the prevention and remedy of vascular dementia might change considerably.” stated.
Nevertheless, he added, “We have to improve the dimensions of future analysis and conduct extra experiments.”
The outcomes of this examine had been printed on the 4th within the American School of Cardiology’s journal ‘Circulation Analysis’.
Kim Ye-seul, Donga.com reporter [email protected]
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2024-06-10 17:28:36