2024-03-19 16:58:00
Human cells extracted from urine show genetic similarities to kidney cells, indicating their potential as a non-invasive diagnostic tool for kidney diseases. This discovery raises the possibility of earlier and easier detection of the disease compared to invasive procedures such as biopsies.
Scientists at the University of Manchester analyzed gene expression in urine cell samples and compared them with gene levels in kidney tissue. Using transcriptomic and computational techniques, the study revealed information about molecular responses in cellular environments by identifying a specific gene (ENPEP) related to high blood pressure in the kidney.
Persistent high blood pressure poses serious health risks, including heart disease, heart attacks, and strokes. Targeting the ENPEP gene could offer new avenues for developing antihypertensive drugs, potentially improving long-term treatment. Advances in understanding genetic links to high blood pressure pave the way for personalized treatment strategies.
The identification of genes such as ENPEP not only helps regulate blood pressure but also opens the doors to personalized medicine in the treatment of hypertension. Investigation of new targets for antihypertensive drugs presents opportunities to improve patient care and treatment outcomes.
Advances like those in this study illustrate the crucial role of genetics in advancing medical interventions for hypertension and kidney health.
The study was published in the journal Nature Communications.
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