There will be blisters on the face and body. but due to diseasemonkey poxIt takes place in poor countries and far from developed countries. Therefore, the problem has not been dealt with as it should be. Despite the Nigerian public health request for assistance from the international community for the smallpox virus outbreak, in 2017 there was an unusual outbreak of monkeypox in Europe. United Kingdom and Israel from people arriving from Nigeria But the disease was able to be calmed down.
WHO declares that the virusmonkey poxNot a contagious virus “through vaginal secretions and sperm during sex” like the HIV virus. or hepatitis C, which can be spread through semen and vaginal fluids (There is no information that monkeypox virus is found in the semen and vaginal fluids of infected people.) But it can be transmitted. “During sex,” as well as the common cold and COVID-19, it is contagious through close contact.
Although in the latest outbreak of the virusmonkey poxIt is spread among men who have sex with men or gay men. It does not mean that it is a contagious disease only among MSM. Everyone, regardless of gender, age, is at risk of contracting the monkey pox virus.
Experts are working on the most plausible explanation for why the virus.monkey poxIt has been able to dodge the radar detection since 2017 until it returned to epidemic in non-African countries in 2022 from infected people with no history of traveling to African countries. especially Nigeria, it is possible that
1. Something happened. Such as large-scale gatherings with large numbers of people, such as the Gay pride rally in Spain, has given some people the chance of spreading the smallpox virus from person to person. When attendees who contracted the infection during the rallies returned to their country of residence, a pandemic followed.
2. Virusmonkey poxThis is an endemic disease that has been spread from animals to humans periodically. Has evolved into a sequence of mutations until it can spread better between people.
3. Virusmonkey poxIt may have spread from person to person for some time but we cannot detect it.
virus outbreakmonkey poxDifferent from the 2019 coronavirus that we are familiar with. For example, each strain (clade) of the 2019 coronavirus, whether it is a major strain or a subspecies. Will gradually spread out to replace each other, for example, Delta Outbreak replaces Alpha and Beta, while Omicron Outbreak replaces Delta, etc.
But the nature of the virus outbreakmonkey poxMany species seem to be able to spread at the same time. Since May 2022, the entire genome of the monkey pox virus has been decrypted in Europe, the Americas and Australia, in Spain, the Netherlands, Finland, Australia, Switzerland, Slovenia. , Italy, Israel, France, Belgium, Germany, United Kingdom, Canada, United States, Portugal: A new strain of monkeypox virus has been found to have a different mutation from the original monkeypox virus that is endemic in Africa. More than 40 locations. However, in many countries, for example, in the case of the US Centers for Disease Control and Prevention (US CDC), entire genomes have been randomly decoded from samples of monkey pox cases across the United States. Between May and June 2022, no less than two strains of the monkeypox virus have been reported concurrently.
The first strain is genetically similar to the one currently prevalent in Europe (2022), where the infected has no history of traveling to Nigeria. The second strain was found to be genetically similar to the strain from a patient returning from Nigeria in 2021. The US CDC estimates that the smallpox virus has been quietly spreading in the United States for some time. It is investigating how many waves of genetic decoding have come into the epidemic. And each wave has different symptoms of infection or not?
If there is an outbreak of the virusmonkey poxOccurring in a country that has never had an outbreak before For example, Thailand needs to quickly investigate genetic decoding within a week. In order to know which species of monkeypox is an outbreak of the monkey pox virus in order to be able to manage, prevent, care and treat accordingly with each species that has come into the epidemic and spread in Thailand
Medical Genome Center There are two types of testing developed:
1. Develop Massarray genotyping as a preliminary screening test. After a positive PCR test, it was possible to screen for and isolate these viruses that cause skin blisters that are indistinguishable from blisters from early-stage monkey pox infection. together in a single test (single tube reaction).
a. Herpes Simplex virus type 1, or HSV-1, is a common blistering infection around or around the mouth.
b. Herpes Simplex virus type 2 or HSV-2 is an infection in the form of blisters in the genital area or genitalia, vagina, cervix, heavy soldier, penis, scrotum, etc.
c. Herpes Simplex virus type 3 or HSV-3 causes chickenpox (varicella) and shingles (herpes zoster) blisters.
d. virusmonkey poxare currently prevalent in Europe, the Americas and Australia, with >40 different mutations from the original monkeypox virus.
e. virusmonkey poxoutbreak in 2017 from Nigeria, Africa, which has not had a different mutation from the original strain of the smallpox virus.
f. The human smallpox virus, which infects adults with a death rate of 30% and in children as high as 80%, is now thought to have been eradicated.
2. Fast decoding of varieties in the manner of “Metagenomic”, which can identify all types and types of microorganisms and viruses, RNA or DNA. from the specimen To know what type of microorganism or virus we are dealing with. especially in the case of virusmonkey poxCurrently, we do not have enough information to determine which strains are infected and how mutations have occurred for timely care, prevention and treatment, as well as to help accelerate the sharing of the smallpox virus genetic code. The entire genome of monkeys is based on the global databases “GISAID” and “Nextstrain” for scientists from all countries to use to help end the smallpox virus epidemic as quickly as possible. to prevent endemic diseases in countries that have never had an outbreak before
Source: Center for Medical Genomics