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Colorectal Cancer in Young Adults: A new Approach to Treatment
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Boston,MA – March 15,2024 – A concerning trend is emerging in the fight against colorectal cancer: a real and concerning increase in the incidence of colorectal cancer in younger adults,” says Kimmie ng,M.D., founding director of Dana-Farber’s Young-Onset Colorectal Cancer Center.”And sadly, these patients often present with more advanced disease.”
Why the Rise in Young-Onset Cases?
The reasons behind this increase are complex and still under investigation. Factors potentially contributing to the trend include changes in diet, lifestyle, and the gut microbiome.There’s also a growing suspicion that the cancers occurring in younger adults may be biologically different from those in older populations.
A New Model of Care at Dana-Farber
Recognizing the unique needs of this patient population, Dana-Farber Cancer Institute established the Young-Onset Colorectal Cancer center.This center isn’t just about treating the disease; it’s about reshaping how research and care are delivered.The center focuses on a multidisciplinary approach,bringing together specialists in gastroenterology,oncology,surgery,and genetics.
“We’ve created a dedicated space where we can really focus on the specific challenges faced by young-onset patients,” explains Dr. Ng. “This includes addressing issues like fertility preservation, genetic counseling, and the psychological impact of a cancer diagnosis at a young age.” The center also prioritizes collecting detailed data and biospecimens from patients to fuel research into the underlying causes and optimal treatments for this form of the disease.
The team is actively investigating whether the molecular characteristics of colorectal cancer differ between younger and older patients. Early findings suggest that tumors in younger adults may be more likely to harbor certain genetic mutations and respond differently to standard therapies. This knowledge is crucial for developing personalized treatment strategies.
“We need to understand why this is happening so we can prevent it,” Dr. Ng emphasizes. “And for those who are diagnosed, we need to ensure they recieve the most effective and tailored treatment possible.”
The center’s work represents a significant step forward in addressing the growing challenge of young-onset colorectal cancer, offering hope for improved outcomes and a better quality of
