LUTS Treatment: Pills vs. Surgery – Which is Best?

by Grace Chen






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BASEL,July 3,2025

Sonography‘s Decisive Role

sound waves offer valuable clues when deciding on treatment.

  • Sonography is a key tool in assessing lower urinary tract issues.
  • It helps determine if bladder obstruction is present.
  • This determination is crucial for deciding between medication and surgery.
  • LUTS are categorized into storage, emptying, and post-miction symptoms.

Lower urinary tract symptoms can significantly impact quality of life; what role does sonography play in evaluating these symptoms? Sonography, or ultrasound, is recommended to assess bladder outlet obstruction, which helps determine whether medication or surgery is the most appropriate treatment.

Expert Insight: Sonography provides a non-invasive way to visualize the bladder and prostate, offering valuable details about their size, shape, and function. This helps clinicians make informed decisions about patient care.
Illustration of the Urinary Tract.

Understanding LUTS and BPH

PD Dr. Malte Rieken from Alta Uro AG in Basel, notes that the term “Benign Prostatic Hyperplasia (BPH)” is actually a histological finding and not a clinical diagnosis. What patients experience are Lower Urinary Tract Symptoms (LUTS).

These symptoms are generally divided into three categories:

  • Storage symptoms
  • Emptying symptoms
  • Post-miction symptoms

Did you know? In most men, BPH is the underlying cause of LUTS.The intersection of LUTS, benign prostate enlargement, and bladder outlet obstruction is referred to as Benign Prostatic Syndrome (BPS).

Clinical Significance: Identifying the specific type of LUTS (storage, emptying, or post-miction) helps tailor treatment strategies to address the patient’s primary concerns.

Navigating Guidelines

The German Society for Urology (DGU) provides S2E guidelines, while the European association of Urology (EAU) addresses the broader topic of LUTS and related conditions.

Guideline Note: Consulting both DGU and EAU guidelines ensures a thorough approach to managing LUTS, incorporating the latest evidence-based recommendations.

Beyond Sonography: Diagnostic Tools and Techniques

While crucial, sonography isn’t the only tool in a urologist’s arsenal for diagnosing lower urinary tract symptoms (LUTS). other diagnostic methods play vital roles in a complete assessment. These techniques complement the findings from sonography, helping to build a complete picture of a patient’s condition.

Additional Tests: Alongside sonography,other assessments add to a complete diagnosis.

Uroflowmetry

Uroflowmetry measures the flow rate of urine. This simple, non-invasive test involves urinating into a special device that records the volume and speed of the urine stream. Uroflowmetry provides valuable insights into how efficiently the bladder empties.

Cystoscopy

Cystoscopy involves using a thin,flexible tube with a camera (cystoscope) to visualize the urethra and bladder directly. This allows the urologist to identify any structural abnormalities, such as strictures, stones, or tumors, within the urinary tract.Cystoscopy is a crucial diagnostic tool for exploring the causes of LUTS. It helps guide treatment decisions.

Pressure Flow Studies

These studies, also known as urodynamic studies, provide a more detailed assessment of bladder function. They measure bladder pressures during filling and emptying.With this details, urologists can determine bladder capacity, detrusor muscle function, and the presence of any bladder outlet obstruction. Pressure flow studies are most useful when the cause of LUTS is not clear, or when considering advanced treatments.

Urinalysis

A routine urinalysis can help to detect urinary tract infections (UTIs), blood in the urine (hematuria), or other abnormalities that may contribute to LUTS. These findings guide treatment decisions.

Prostate-Specific Antigen (PSA) Test

In men, a PSA test may be conducted to screen for prostate cancer. Elevated PSA levels can sometimes be associated with BPH, wich, as discussed, is often the underlying cause of LUTS. This test is particularly vital in men to rule out other serious conditions.

These diagnostic tools work together to comprehensively evaluate LUTS. A urologist selects the most appropriate tests based on an individual’s symptoms, medical history, and initial findings from sonography and physical examination.

Complementary Approach: Combining different diagnostic methods to provide more accurate assessments that can guide a personalized treatment plan.

Treatment strategies Based on Diagnosis

Once the diagnosis is confirmed through sonography and other assessments, the urologist will formulate a personalized treatment plan. The choice of treatment depends on the severity of the symptoms, the underlying cause, and the patient’s overall health and preferences [[3]].

Treatment options will always be tailored as the causes of LUTS are so varied.A variety of options, including medication, lifestyle changes, or surgical intervention, are used to solve the issues.

Medications

medications often form the basis of the treatment plan. Alpha-blockers help relax the muscles in the prostate and bladder neck, which improves urine flow. 5-alpha reductase inhibitors shrink the prostate, reducing obstruction over time. Anticholinergics and beta-3 adrenergic agonists help control overactive bladder symptoms. According to current research,desmopressin is used for nocturia [[1]].

Lifestyle Modifications

Simple lifestyle changes can also improve symptoms. Limiting fluid intake before bed, avoiding caffeine and alcohol, and practicing timed voiding are frequently enough recommended. Dietary changes may also help; such as, avoiding bladder irritants.

minimally Invasive Procedures and Surgery

for more severe cases, minimally invasive procedures, such as the UroLift System or GreenLight laser therapy, or surgery, such as transurethral resection of the prostate (TURP) may be considered [[2]]. These procedures aim to relieve bladder outlet obstruction and improve urinary flow.

Treatment Choices: Treatment relies on the severity of symptoms, the underlying cause, and the patient’s overall health and preferences.

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