A “humanized” pig kidney model makes xenotransplantation increasingly realistic

by time news

2023-10-11 18:44:14

Macaques given genetically modified pig kidneys have survived for up to two years.

Publications are accumulating, and transplanting organs from genetically modified animals seems more and more realistic. Researchers from Harvard University and the American company eGenesis publish in the scientific journal Nature the results of transplants carried out on non-human primates with a pig kidney model comprising a unique combination of genetic modifications. The survival times obtained (up to two years) are the longest to date. Data that could pave the way for human trials in the coming months, if the FDA, the American medical regulatory authority, gives the green light.

A real chance of survival

The race is accelerating between research groups working on kidney xenografts. And this publication could mark an important turning point. “This is an excellent article and I think it will make a big splash», comments Valentin Goutaudier, nephrologist and researcher at the Institute of Organ Transplantation and Regeneration

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