Tyrosine & Lifespan: Popular Supplement Linked to Shorter Life in Men
Table of Contents
A new study suggests a potential downside to popular energy and focus supplements, revealing a correlation between tyrosine consumption and a reduced lifespan in men. Researchers from the University of Georgia (UGA) and Hong Kong have uncovered data indicating that regular tyrosine intake may be associated with a one-year decrease in longevity.
We frequently enough operate under the assumption that products sold in stores are inherently safe, but this isn’t always the case. From the food we eat to the beverages we drink, unintended consequences can lurk in unexpected places. This is notably true for those pushing their bodies to the limit – extreme sports enthusiasts, “neuro-hackers,” and dedicated gym-goers – who may be unknowingly exposing themselves to hidden risks.
The study, analyzing data from over 720,000 men in the UK Biobank, highlights the potential dangers of certain amino acids. Researchers found that increased levels of tyrosine were correlated with a shorter lifespan. While another amino acid, phenylalanine, showed no such link, tyrosine consistently appeared to be associated with a reduction in longevity – currently estimated at one year.
Where is Tyrosine Hiding?
Tyrosine is a popular ingredient in many pre-workout supplements, nootropics (cognitive enhancers), and energy drinks, frequently enough marketed to improve focus, alertness, and physical performance. It’s also found in some multivitamins, which can have their own stimulating effects.)
Beyond tyrosine: The “Biochemistry Casino”
This research underscores a broader concern: the potential for unforeseen consequences within the world of vitamins and supplements. Studies have shown correlations between excessive intake of certain nutrients and adverse health outcomes. Such as, 400 IU of Vitamin E per day has been linked to a 19% increased risk of prostate cancer, while excessive Vitamin D intake is associated with cataracts. Supplementing with Vitamins A, C, E, and Beta-Carotene has also been associated with worse outcomes for the gastrointestinal tract.
As one doctor observed,”Maybe the clever doctors who tell you to just get all your vitamins and minerals from your food aren’t that wrong?”
The Adrenaline Connection & Protein Intake
Researchers are still working to understand the exact mechanism behind tyrosine’s potential impact on lifespan. Tyrosine is a precursor to both dopamine – the “go-go” hormone – and adrenaline – the “run like hell” hormone.The team theorizes that the increased adrenaline and noradrenaline levels resulting from tyrosine consumption could contribute to chronic stress, which is known to accelerate aging.
Furthermore, tyrosine is derived from protein, and men generally consume more protein than women. The researchers recommend being mindful of protein intake, particularly in relation to age-related recommendations. The USDA’s Recommended Dietary Allowances (RDAs) are:
- Average sedentary person: 0.8g/kg of body-weight/day
- Moderate activity person: 1.3g/kg
- Intense physical activity person: 1.6g/kg
Interestingly, individuals in early and later life are frequently enough advised to consume higher amounts of protein than those in middle age. While 1g/lb of body weight or more is a common guideline for weightlifters and bodybuilders, some fine-tuning may be necessary. Notably, the study also found that some protein reduction is associated with a longer lifespan, adding another layer of complexity.
Ultimately, the study serves as a reminder that even seemingly innocuous supplements can have unintended consequences. As the researchers concluded, the candle that burns twice as luminous may not burn half as long, and some things we take for granted may come with a cost.
• Source: EurekAlert
• Source Study: Aging – The role of phenylalanine and tyrosine in longevity: a cohort and Mendelian randomization study
