2023-12-06 00:28:51
Live with high cholesterol levels can increase the risk of developing a heart disease o one cerebrovascular accident. However, it does not usually cause warning symptoms until complications occur. Given this, a group of researchers has developed the medicine VERVE-101, the first drug to modify DNA to reduce cholesterol levels.
What is VERVE-101 and what is it for?
He medicine VERVE-101 It is the first drug used by CRISPR genetic technology (Clustered Regularly Interspaced Short Palindromic Repeats) to modify the genetic material of an organism in a controlled manner in order to achieve various objectives, in this case, reduce cholesterol levels to prevent long-term health problems.
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I agree with you results of a phase 1b clinical trial published by the pharmaceutical company Verve Therapeutics, the use of VERVE-101 has managed to modify the PCSK9 gene in the liver, which encodes an enzyme relevant to the regulation of receptors colesterol LDL in hepatocytes to reduce elevated LDL cholesterol levels.
Currently, the clinical trial is being carried out in patients at high risk of hypercholesterolemia heterozygous familial (HeFH), which also present atherosclerotic cardiovascular disease established and uncontrolled levels of “bad cholesterol”, related to serious heart health problems.
Preliminary results suggest that single-use treatment injection with VERVE-101 can keep low LDL cholesterol level permanently in people with HeFH, achieving a reduction of up to 55 percent in one case.
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How does VERVE-101 cholesterol-lowering medication work?
He medicine VERVE-101 He stands as a pioneer of the medical revolution. Through a single injection, he reaches the core of the liver cellspermanently silencing the gene PCSK9the culprit behind the elevated cholesterol levels “bad” in our blood.
This advance in medicine promises to not only transform the lives of those suffering from hypercholesterolemiabut also improve the cardiovascular health with a single dose.
Until now, the medicine VERVE-101 has become a hope in the fight against heart disease by showing that it could keep LDL cholesterol levels under control for life with an intervention as simple as an injection.
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Where do you get VERVE-101 to lower cholesterol?
He medicine VERVE-101 to reduce cholesterol It is still in clinical trials, which is why it is not yet available on the market. The team of the pharmaceutical Verve Therapeutics works to begin phase 2 by 2025.
At this stage, an expansion of the drug is planned not only to people who are at high risk for the disease, but also to those who are in the early stages of their diagnosis.
As you can see, this medicine could become a great ally in the fight against heart diseases. What do you think?
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