“Dr. Yong” reveals information about the subunit protein vaccine. used with Thai people
Date 08 May 2022 time 09:20
“Prof. Dr. Yong Phuworawan” gives information about the COVID vaccine subunit protein type that have been used with Thai people Point out that the ingredients are something new, just starting to be used in humans. Must follow up on safety as well.
Prof. Dr. Yong Phuworawan, head of the center specializing in virology Clinic, Department of Pediatrics Faculty of Medicine Chulalongkorn University comment on covid 19 vaccine Types of protein subunit (protein subunit) with interesting content as follows
now Thailand There is a type 4 vaccine available to the Thai population. It is a protein subunit, Covovax vaccine from India. It is a licensed vaccine and method like Novavax vaccine in the United States.
subunit protein used to make the covid vaccine It’s not a new principle. This vaccine is already in use, for example the hepatitis B vaccine is in use a lot.
But covid-19 protein sprites will be large, stimulating immunity. Therefore, special techniques are required. To be an additional aid is to use an adjuvant or a booster to boost immunity. come as a component
The protein subunit Chinese vaccine ZF2001, trade name Zifivax, was developed by Anhui Zhifei Longcom. The injection therefore requires up to 3 needles and the landscape is not very high.
The vaccines to speak of are Novavax and Covovax which are available in Thailand. use the same principle Let living things make proteins. like that of the covid virus protein sprite.
The focus of this vaccine is that the adjuvant uses Matrix M adjuvant as a saponin derived from the bark of the Molina tree. It is new and has recently been used in this vaccine. It has not been used in humans before. Therefore, it has been studied from Phase I to Phase 3 and has been used. Its use as a stimulant is not yet known. It can be seen that this vaccine has passed Phase 3 for a year and a half. has just been put into practice.
another vaccine To be mentioned is the tobacco leaf vaccine. protein made from tobacco leaves The vaccine is Medicago, Canada. The vaccine, trade name Covifenz, is based on GSK’s ASO3 inhibitor. in cervical cancer vaccine stimulate high immunity and have confidence in the matter of safety and successfully passed the 3rd phase of the experiment It was about 70 percent effective in preventing disease, reducing moderate and severe disease severity by 78.8 percent.
Barriers to protein-based vaccines It’s not about making proteins from living things. The big problem lies in enhancing substances. Stimulate immunity (adjuvant) that is used. good performance Will be licensed, such as Matrix M, ASO3. Matrix M is a new thing, just started to be used in humans. There must be a follow-up on safety issues.
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