2024-02-02 11:13:13
Tecan is proud to offer end-to-end Salomica workflow solutions, including cell seeding and culture with quality control and monitoring, through drug dosing to live cell imaging and analysis. This comprehensive offering enables laboratories to improve the reliability, reproducibility and productivity of their workflows while addressing key challenges in the growing field of 3D cell biology.
Complex 3D cell models – such as spheroids, organoids and organ-on-a-chip systems – have great potential in many applications, from drug development to personalized medicine research. Lack of reproducibility is still a challenge in many of these workflows. Automation is key to overcoming this problem, helping labs increase productivity and achieve consistent and reliable workflows.
Tecan’s cellomics portfolio includes the recently launched Uno Single Cell Dispenser™, a compact, automated device that provides single cell isolation and reagent dispensing in a single system. This cost-effective device allows researchers to transfer single cells to a 384-well plate in approximately 5 minutes while maintaining a robust 90% cell viability for downstream analyses.
Central to Tecan’s offering for Salomics is the Fluent®, an automatic fluid handling workstation. Optimized for cell culture maintenance, cell seeding, and medium exchange (6- to 1,536-well plates), the system handles complex matrices such as Matrigel® with ease and offers truly scalable workflows through the combination of centrifuges, incubators, and peripherals. To automate the generation of dose response curves, synergy experiments and serial dilutions, the D300e digital instrument provides automatic dispensing from picoliter to microliter scales, empowering both small and large drug discovery.
Tecan’s flagship multimode reader, the Spark® Cyto, has been specifically designed for automated monitoring of assay measurements of live cell cultures. Its imaging systems, which include both brightfield and fluorescence capabilities, and its full environmental control (temperature and gas), support whole-well imaging of microplates and uninterrupted cell growth for rapid analysis and reliable results. Combining multiple plate reading and cell image analysis in one instrument improves test reproducibility and results reliability. It also provides more insight, including assessment of ATP levels and spheroid growth.
In a planned 2024 update, the introduction of AI-based 3D analysis tools for Spark Cyto will further enhance the capabilities of this device. The tools will open up new possibilities for scientific research by improving the efficiency, accuracy and depth of insights that can be derived from experiments.
Automated workflows are key in any Salomics laboratory, and the latest additions to our Salomics product portfolio reinforce Tecan’s position as a leading supplier to this important sector. Obtaining seamless end-to-end solutions from a single provider allows us to fulfill our goal of empowering our customers to focus on accelerating research and expanding important innovations in healthcare.”
Luca Vallegia, Senior Vice President of Laboratory Automation, Tecan
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