Korrie Stevenson, a 51-year-old mother of two from Winter Park, Florida, described feeling disconnected from joy for months despite having no clinical diagnosis of depression.
She would see a beautifully decorated birthday cake or watch a pink-and-purple sunset but perceive unable to truly enjoy the moment, describing the sensation as simply “meh.”
Her experience aligns with a growing number of reports from patients taking GLP-1 medications like Ozempic, Wegovy, Mounjaro, and Zepbound who say their emotional responsiveness has dulled—not just to food but to hobbies, music, and even intimacy.
How GLP-1 drugs may affect emotional reward pathways
One theory, cited in The Washington Post, is that GLP-1 drugs reduce activity in brain regions associated with reward, which helps curb cravings for food, alcohol, and nicotine but may inadvertently blunt other sources of pleasure in some individuals.
For more on this story, see Ozempic Personality: How GLP-1 Weight Loss Drugs Affect Relationships and Sex.
Why some users continue taking the drugs despite being underweight
Even as medical guidelines suggest GLP-1 agonists are intended for obesity or type 2 diabetes, many people with normal or low body mass index are seeking the drugs, driven by cultural pressures and personal perceptions of weight.
What Hollywood’s weight trends reveal about off-label use
