In the past, it was not possible to detect dengue virus in patients. In medical practice, only observing the lesions can provide symptomatic treatment. Monitor platelet count and red blood cell concentration and confirmed that he was actually infected with the dengue virus From the immune level test against the dengue virus When the patient has better symptoms and the fever is reduced, but now with modern medical technology enabling doctors to detect infectious diseases from blood with laboratory tests
Emeritus Professor Dr. Ampaiwan Chuan Sumrit, Lecturer at the Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University found a new alternative inDengue virus diagnosis orDengue fever with ELISA (Enzyme-linked Immunosorbent assay) that uses the patient’s urine instead of blood
This is a method that has already been registered with a petty patent. After being trialled in dengue-infected patients with less severe symptoms, called “Dengue fever in febrile phase” was found to give an accurate result of 68.4%.
and dengue-infected patients with more severe symptoms, referred to as “dengue hemorrhagic fever”, with 63.9% accurate results. which can be used as an alternative method for diagnosing dengue infection to find indications for dengue virus infection in the initial stage
from such method Although it provides results that can be used to make a preliminary diagnosis. But in the case of a negative test result, the patient’s condition must be closely monitored.
and with personnel and budget constraints Therefore, the ELISA method in the laboratory Specimen samples are required. Simultaneously, at least half of the well plate (plate), which has a total of 96 sample wells, must collect all specimens before they can be examined.
Which causes longer waiting time than the strip method, which can know the results of specific examinations and faster, but gives accurate results 47.2 – 52.6% lower than the ELISA method
The immune test against dengue virus still the standard method The total blood was tested twice, the first time in the fever stage and the second time at least 2-4 weeks away from the first time to compare immunity against dengue virus. “Primary infection” (there is a chance of re-infection with dengue) or “Secondary infection” (there is a very low chance of re-infection with dengue).
The risk of dengue infection depends on many factors. Especially according to the differences in the genetic material of each person. people of different nationalities There will be different responses to the infection.
In addition, Professor Emeritus Dr. Ampaiwan Juansamrit Also expressed concern about the trend of dengue infection of the world’s population in the present era has changed.
It was found that even in places where dengue virus outbreaks have not been seen before, may have transmitted dengue virus from people who have traveled to places There is an outbreak of dengue virus. dengue virus infection without any symptoms
Mosquitoes carry the infection from an infected person. The incubation period in infected mosquitoes is 7 days before transmission to uninfected individuals bitten by infected mosquitoes. Therefore, be extremely careful not to be bitten by mosquitoes.
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Interview and news writing by Thitirat Dechprom, public relations (specialized in corporate communication) General Administration Division office of the president Mahidol University Tel. 0-2849-6210
Source: press release