Philadelphia Eagles running back Saquon Barkley faces testing after exiting Sunday’s 24-20 loss to the Los Angeles Rams with a hamstring injury, leaving his availability for an upcoming London game uncertain as head coach Nick Sirianni promises more updates on Wednesday.
The Philadelphia Eagles dropped a tight 24-20 contest to the Los Angeles Rams at Lincoln Financial Field, but the scoreboard proved secondary to a mounting physical toll across the roster. Star running back Saquon Barkley left the game in the first quarter after a six-yard carry, walking gingerly to the sideline before heading to the locker room (according to reporting from A to Z Sports). The team officially ruled him out before halftime.
Head coach Nick Sirianni addressed reporters the following day without a definitive timeline for his All-Pro running back. The team awaits further medical evaluations to determine whether Barkley will make the trip across the Atlantic for Week 5 against the Jacksonville Jaguars in London (as detailed by Sportsnaut).
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“Yeah, we’ll see. These guys are going through different things with treatment and all those different things. We’ll see how everything responds and then have more answers for you probably Wednesday on that stuff. I know he’ll do everything he can do to get himself back, and obviously, he’s a great player and a great teammate. We always need him on the field.”
Nick Sirianni, Philadelphia Eagles Head Coach
Barkley reached for his right leg and grabbed his right hamstring immediately following the opening-quarter rush, grimacing as trainers escorted him toward the medical area. NFL Network’s Ian Rapoport reported that early evaluations indicate the soft-tissue concern does not seem to be overly serious,
though hamstring strains carry a notoriously high risk of lingering. Before departing, Barkley carried twice for eight yards and caught one pass for two yards. The setback compounds a difficult stretch for the veteran runner, who entered the afternoon wearing a protective cowboy collar to manage a persistent stinger that previously limited him during a Week 2 victory over the Tennessee Titans.
Reflecting on the unpredictable nature of athletic injuries, FOX broadcast analyst Tom Brady noted from the booth that wet conditions at Lincoln Financial Field may have contributed to the sudden ailment as players planted and drove hard before their bodies were fully warmed up. Throughout his career, Barkley has established an extensive rushing resume, most notably during Philadelphia’s 2024 Super Bowl championship run when he amassed 2,005 yards on 345 carries and scored 13 touchdowns. Following a production dip last season where he posted 1,140 yards on 280 attempts, he returned to the 2026 campaign looking to reestablish his elite form.
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Tank Bigsby Sent to Injured Reserve Following Core Muscle Surgery
The backfield situation compounded rapidly when Barkley’s primary backup also suffered a severe setback during the fourth quarter. Tank Bigsby carried the ball 14 times for 55 yards after stepping in for Barkley, but he exited late in the game with an apparent groin injury (Sports Illustrated reported). Subsequent medical reporting revealed that Bigsby requires core muscle surgery and is headed to injured reserve (<a href="https://www.delawareonline.com/story/sports/nfl/eagles/2026/10/05/eagles-saquon-barkley-injury-update-cam-jurgens-moving-back-to-center/92098405007/).
Shipley finished the Rams game with six rushes for 23 yards.
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The News Journal). Through three-plus appearances this season, Barkley has accumulated 36 carries for 182 yards.
The offensive depth chart faced heavy strain even before kickoff against Los Angeles. Wide receiver DeVonta Smith was ruled out with a hamstring injury, tight end Dallas Goedert missed time with a knee issue, and right tackle Lane Johnson was a late scratch for personal reasons (CBS News confirmed).
Sirianni emphasized that the franchise refuses to use health setbacks as an excuse for offensive execution flaws four weeks into the year (CBS News added).
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“I don’t think we felt that way when we had the opportunity to make it a three-score game. I’m not going to make excuses. I’m not going to make promises. I’m just going to double down on the work and lead the best way I can and continue to have the confidence that I have in this group to forge and figure it out.”
Nick Sirianni, Philadelphia Eagles Head Coach
which will leave the team without its primary backup for a significant portion of the upcoming season.
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More on Saquon Barkley
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