2023-12-01 22:27:10
Today, the Pfizer pharmaceutical announced, through a statement, the decision not to continue with advanced phase studies in the testing of two doses a day of the medicine danuglipron, an oral weight loss drug that was expected to compete with Ozempic. However, the majority of study participants had side effects.
What is danuglipron medicine?
He danuglipron medicine It is an oral drug to treat obesity, promoting weightloss, which was in clinical trial. However, after trial participants took high doses for 16 weeks, they reported some side effects.
Although it was expected to complete the last stage program of danuglipron By the end of this year, today, the pharmaceutical company Pfizer reported that he will not continue with the late phase studies; Instead, it will choose to focus on developing a danuglipron version modified release, which can be administered once a day to reduce the adverse effects that may develop.
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Is the drug danuglipron useful for weight loss?
According to current study with the two-pill-a-day version, Pfizer stated that the danuglipron medicine Yes, it is effective for losing weight, since it managed to meet its main goal of reduce weight in adults with obesity and without type 2 diabetes.
Los weight loss results average observed in the trial show that weight reduction ranged from 6.9 percent to 11.7 percent in patients taking the drug for 32 weeks, compared to a 1.4 percent weight gain in the placebo group .
However, the researchers reveal that this performance contrasts with the significant decrease of almost 15 percent observed with the highest dose of the orforglipron experimental pill once a day, developed by Eli Lilly, after 36 weeks of treatment in a trial with patients suffering from obesity or overweight.
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What side effects did the drug danuglipron cause?
Pfizer noted that during the taking two pills of the drug danuglipron Side effects were observed at elevated rates compared to the placebo group. In the study, 73 percent of participants experienced nausea, 47 percent vomiting, and 25 percent diarrhea.
However, Pfizer assured that no new safety problems were identified during the trial. Therefore, it will seek to perfect the formula of the medication in order to reduce adverse effects to guarantee the safety of those who take it.
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