A new blood test allows early detection of Alzheimer’s

2024-01-23 14:11:07
A few years ago the only possibility of diagnosing Alzheimer’s was to perform a post-mortem study of brain samples. Later, effective biomarkers were found that allow it to be identified with cerebrospinal fluid and now research has allowed it to be detected early with a blood test. The results of this test have just been published in the journal JAMA Neurology, in which researchers from the Neurological Diseases, Neuroscience and Mental Health Research Area of ​​the Sant Pau Research Institute have participated, led by Dr. Juan Fortea, director of the Memory Unit of the Neurology Service of the same hospital. Research shows that the p-tau217 protein in blood offers comparable precision to biomarkers in cerebrospinal fluid and was shown to be particularly effective in detecting longitudinal changes, even in early stages of the disease. Related News standard Yes The largest bank of ancient DNA in the world reveals the origin of diseases such as Alzheimer’s or multiple sclerosis José Manuel Nieves standard No World Day These are the first two signs of Alzheimer’s for an early diagnosis ABC Less invasive alternative A highlight of blood tests is their ability to significantly reduce the need for additional confirmation, reducing by 80 percent the number of tests required to confirm the diagnosis of Alzheimer’s. Dr. Daniel Acolea, researcher in the Neurobiology of Dementia Group at the Sant Pau Research Institute, explains that “this biomarker has shown very high performance in detecting Alzheimer’s in the blood, with an accuracy of between 90 and 95 percent.” . Of all the biomarkers that are currently being studied to diagnose Alzheimer’s disease, this is the one that has given the best results. This discovery, in the words of experts, can open new doors in research and treatment of the disease, offering accessible and reliable tools for both healthcare professionals and patients. “It offers a much more accessible and less invasive alternative for the early diagnosis and monitoring of Alzheimer’s,” explains Dr. Alberto Lleó, researcher in the Dementia Neurology Group at the Sant Pau Research Institute.
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