California Sees Increase in Mpox Cases: Virus Evolving to Become More Infectious, Research Shows

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Title: Rising Cases of Mpox in California and Concerns over Virus Evolution

Subtitle: California’s Gay-Friendly State Sees Increase in Infections; UK Research Indicates Mpox Becoming More Infectious

Date: [Insert Date]

California, one of the most gay-friendly states in the US, is witnessing a surge in Mpox cases, a viral infection formerly known as monkeypox. Rates have been steadily increasing, with the state’s public health department reporting 17 new cases per week, compared to less than seven cases in August. As a result, healthcare providers have been alerted to remain vigilant against the outbreak.

Although cases of Mpox were extremely rare in the US and Europe before spring 2022, there was a significant outbreak last year, primarily affecting gay and bisexual men. While the outbreak subsided towards the end of the year, recent data suggests a resurgence, particularly in California.

Dr. Tomás J. Aragón, the state’s public health director, stated, “We are beginning to see an uptick in Mpox cases across the state. With this, we are reminding and encouraging all Californians to be aware of the signs and symptoms of Mpox and to take preventive measures, including vaccination, to protect against severe illness.”

According to health officials, receiving the mpox vaccine in two doses, spaced around a month apart, provides the best protection against the virus. Although the vaccine is not foolproof, individuals who are vaccinated are likely to experience milder symptoms compared to those without vaccination.

However, a concerning trend has emerged as around 40% of individuals who received the first dose of the vaccine did not return for the second. The San Francisco Department of Health emphasized the importance of completing the two-dose vaccine series and urged individuals to obtain their second dose.

Since the outbreak began in 2022, the Centers for Disease Control and Prevention (CDC) reported over 31,000 cases and 55 deaths in the US, primarily among immunocompromised individuals. In 2023 alone, there have already been 935 cases of Mpox in the US.

In a separate development, researchers from the University of Edinburgh published a report in Science suggesting that the Mpox virus is rapidly mutating. Prior to the 2022 outbreak, human cases of Mpox were largely due to animal transmission. However, the researchers believe the increased human-to-human transmission is affecting the virus’s evolutionary path.

The study identified specific mutations in a crucial part of the virus’s genetic code, which is targeted by an enzyme in the human immune system that inhibits viral replication. If the virus becomes more resistant to this enzyme through further mutations, it has the potential to become more infectious.

Public health experts continue to emphasize the importance of receiving both doses of the vaccine to minimize the risk of falling ill. It is strongly advised to consult healthcare providers for further guidance and information regarding vaccination against Mpox.

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