Samsung Seoul Hospital Professor Shin Dong-wook and Cho In-young’s research team
Announcement of analysis results of 264,250 cancer survivors
The risk of developing diabetes is highest in those who are obese.
A domestic study found that losing weight after treating cancer reduces the risk of diabetes. Diabetes promotes the growth of cancer cells and increases the rate of recurrence.
According to Samsung Seoul Hospital on the 7th, the research team of Professors Shin Dong-wook and Jo In-young of the Department of Family Medicine, Professor Hye-yeon Koo of the Department of Family Medicine at Seoul National University Bundang Hospital, and Professor Kyeong-do Han of the Department of Information, Statistics and Actuarial Science at Soongsil University announced the impact of weight change after cancer diagnosis on the development of diabetes. .
Diabetes is so dangerous for cancer patients that there are reports that the death rate increases by more than 1.4 times when cancer patients have diabetes. Using data from the National Health Insurance Service, the research team targeted 264,250 patients diagnosed with cancer between 2010 and 2016: ▲group who maintained normal weight before and after cancer diagnosis, ▲group who were obese but then changed to normal weight, ▲group from normal weight. The group was divided into a group that became obese and a group that remained obese for comparative analysis.
Based on body mass index (BMI), obesity was classified as obesity if it was 25 kg/m2 or more, and normal weight if it was lower than this.
According to the research team, 163,395 people, or 61.8% of the total, maintained normal weight, and 7.4%, or 19,558 people, went from obese to normal weight. 14,625 people (5.5% of the total) went from normal weight to obesity, and 66,672 people (25.2%) remained obese even after being diagnosed with cancer.
The group that maintained a normal weight usually had a high proportion of women and was relatively young. The group that maintained normal weight and the group that regained normal weight from obesity also tended to smoke and drink less and exercise regularly. In contrast, groups that remained obese or gained weight were characterized by high rates of smoking and drinking.
During the average follow-up period of 4 years, 12,196 people, or 4.6% of all cancer patients, were newly diagnosed with diabetes.
Based on the group that maintained a normal weight, the risk of developing diabetes was highest in the group that continued to be obese, increasing 2.17 times, and in the group that went from normal weight to obesity, the risk also increased by 1.66 times. If you were obese and then lost weight, the increase was 1.29 times higher, confirming that obesity increases the risk of diabetes.
In fact, in another study, 3,200 patients participated in a diabetes prevention program and lifestyle modifications were conducted with the goal of at least 7% weight loss. As a result, the number of diabetes cases decreased by 58% compared to the control group.
Professor Hye-yeon Koo, co-first author, said, “The results of the study showed that obesity and weight changes can have a significant impact on the development of diabetes at all times before and after cancer diagnosis,” adding, “In particular, breast cancer patients lose weight due to chemotherapy and changes in lifestyle. “As this is increasing frequently, we need to be more careful,” he said.
Professor Cho In-young, co-corresponding author, said, “If you remain obese after a cancer diagnosis, it can easily lead to metabolic diseases such as diabetes,” and “As maintaining an appropriate weight is helpful in cancer treatment, active weight management at the time of cancer diagnosis is recommended when necessary.” “We have to put in effort,” he said.
The results of this study were published in the latest issue of ‘Cancer Research and Treatment (IF=4.6).’
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2024-10-07 17:03:48