What is Sulforaphane and what benefits does it have for health?

2024-03-18 10:30:33

Sulforaphane is a phytochemical naturally present in plants.which belongs to the isothiocyanate family, and is the aglycone metabolite of glucoraphanin.

Its precursor glucosinolate in the form in which it is frequently found in cruciferous plants in which it is especially present, and that by the action of the enzyme myrosinase, which occurs During chewing or cutting the plant, it reacts by transforming it into sulforaphane.

On a nutritional levelsulforaphane has been attributed properties traditionally associated, in general, with cruciferous; Part of these properties have been considered dependent on the sulforaphane content of the plant, therefore, this, a highly appreciated compound in relation to positive properties on the immune system, anti-inflammatory, antineoplastic, and antioxidantand other types.

Sulforaphane is considered a compound with potential positive effects at:

• Neurological.
• Metabolic.
• Oncological.
• Cellular (especially mitochondrial).

[/tie_list]

Properties of Sulforaphane

Sulforaphane has potential positive properties on the functioning of the immune systemon cell protection (including possible properties antiaging), and about the protection against neoplasms.

All these factors are linked to its antioxidant mechanisms.

He sulforafanoas indicated in the review study by Houghton (2019), has a revealing role in the field of nutraceuticals for prevention and management of chronic diseasesand all its mechanisms, or at least, most of the known ones, are mediated by the REDOX influence that the compound has, acting as a catalyst between Reduction-Oxidation reactions.

Some positive mechanisms of action are mediated at the genetic level, especially by the induction action exerted on the Nrf2 system, acting broadly as a cellular protection system in the tissues where it is expressed (kidneys, skeletal muscle, lungs, heart, liver and brain).

What foods contain sulforaphane?

Foods that contain sulforaphane are mainly cruciferous vegetables, notably: Brussels sprouts, mustard seeds, kale, cabbage and broccoli sprouts as the most concentrated source.

The way to release sulforaphane is by altering glucoraphanin, which is the form in which it is naturally present, something that is achieved simply cutting the plant, or chewing it.

The sulforaphane content in plants is variable depending on multiple growing conditionssuch as soil, exposure to sun, heat, and humidity; as well as its cooking and subsequent processing Harvesting affects its sulforaphane content, since this compound is very unstable:

It is unstable to liquid media, so boiling broccoli, for example, is a way to significantly degrade its sulforaphane content.

It is also unstable to heat, in general, so the cooking techniques that best adapt to the consumption of cruciferous vegetables to enjoy the properties of its sulforaphane content are directly the raw consumption of plants, or low-temperature cooking techniques without direct contact with water, such as sous vide.

This makes the use of sulforaphane food supplements has gained special relevance, given the difficulties that exist for its stable management in a traditional kitchen.

Sulforaphane in Supplements

Sulforaphane food supplements are a real X-file on the market, since although many products are offered as “sulforaphane”, They are not really sulforaphane, but its precursor, glucoraphaninwith the enzyme myrosinase that converts them into sulforaphane, but They should not cost what a sulforaphane costs nor do they have the properties of the compound as such, since they do not contain it but contain the operation that results in it.

At HSN we investigate the market for sulforaphane raw materials before launching into manufacturing our supplement.since we are known for being a reference in terms of quality in the supplementation industry, and as such, with a compound as exclusive and delicate as sulforaphane, we were not willing to offer anything that is not the best.

We use the raw material Sulfodyne® a development of the company Ingood by Olga, which offers a standardized broccoli seed extract to 5% stable authentic sulforaphanebeing the only raw material in the world that is capable of ensuring the stability of its patented sulforaphane content.

This transfers to quality, HSN sulforaphane is up to 7 times more bioavailable than other dietary supplements on the market manufactured from glucoraphanin; and the HSN dose has been adapted to the highest contribution in the effectiveness range recommended by Ingood by Olga according to her studies: 400mg of Sulfodyne® per day.

Broccoli Sulforaphane 10mg (200mg Sulfodyne®) from EssentialSeries

Sulfodyne® is the best raw material on the market to administer sulforaphane

Buy it from a quality manufacturer like HSN that offers you a reference productwith the best care in handling the raw material, and the development of vegan and high-concentration encapsulations, according to the conditions of use analyzed by the developer of the patent, who is the one who has carried out the most studies to determine the optimization of the dosage of their product, something that many manufacturers do not respect since they prefer to reduce costs, even affecting the quality of their food supplement.

At HSN we don’t do that, we offer premium quality at the right price.

Sulforaphane and its contraindications

Sulforaphane is a completely safe compound at recommended daily doseshas no associated contraindications and does not require special considerations for its consumption beyond those established on the product labeling, in relation to its contribution (quantity) and method of use (distribution of doses).

It should be noted that if you are a person who has a relevant medical condition, or is receiving medication treatment for a condition, it is preferable seek medical advice who knows the case so that he can assess the compatibility of dietary supplementation with sulforaphane.

Conclusion

Sulforaphane is an excellent compound from the isothiocyanate family, found in cruciferous vegetables, for improving health.

Sulforaphane stands out for:

• Be very sensitive to cooking and treatment as a food supplement.
• Have important antioxidant properties.
• Support metabolic, immunological and neurological health.
• Being a compound with research, currently very active, in relation to cancer and its prognosis.

Recommended bibliography

Asif Ali, M., Khan, N., Kaleem, N., Ahmad, W., Alharethi, S. H., Alharbi, B., … Sharifi-Rad, J. (2023). Anticancer properties of sulforaphane: current insights at the molecular level. Frontiers in Oncology, 13, 1168321. https://doi.org/10.3389/fonc.2023.1168321

Houghton, C. A. (2019). Sulforaphane: Its “Coming of Age” as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease. Oxidative Medicine and Cellular Longevity, 2019, 2716870. https://doi.org/10.1155/2019/2716870

Kim, J. K., & Park, S. U. (2016). Current potential health benefits of sulforaphane. EXCLI Journal, 15, 571–577. https://doi.org/10.17179/excli2016-485

Mahn, A., & Castillo, A. (2021). Potential of sulforaphane as a natural immune system enhancer: A review. Molecules, 26(3). https://doi.org/10.3390/molecules26030752

Ruhee, R. T., & Suzuki, K. (2020). The integrative role of sulforaphane in preventing inflammation, oxidative stress and fatigue: A review of a potential protective phytochemical. Antioxidants, 9(6), 1–13. https://doi.org/10.3390/antiox9060521

Santín-Márquez, R., Alarcón-Aguilar, A., López-Diazguerrero, NE, Chondrogianni, N., & Königsberg, M. (2019). Sulforaphane – role in aging and neurodegeneration. GeroScience, 41(5), 655–670. https://doi.org/10.1007/s11357-019-00061-7

Zambrano, V., Bustos, R., & Mahn, A. (2019). Insights about stabilization of sulforaphane through microencapsulation. Heliyon, 5(11), e02951. https://doi.org/10.1016/j.heliyon.2019.e02951

Related Entries