Siriraj Clinical Research Center Open usage research report “Favipiravir” (Favipiravir) for PatientsCovid-19 with mild or moderate symptoms which has recommendations about taking the drug
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in “Covid-19 Situation” with the number of infected people increasing every day The Siriraj Clinical Research Center would like to bring the results of a research study on the use of “Favipiravir” for the patientCovid-19 with mild or moderate symptoms
The center talks about the research method that An open, randomized, phase III study in COVID-19 patients. with mild symptoms and no pneumonia Comparisons between groups received “Favipiravir” Twice daily, 1,800 mg/dose on the first day and 800 mg/dose on the following day (62 patients) and controls (31 patients). by looking at the temperature respiratory rate heartbeat, blood pressure, oxygenation in the body
study results
- Patients in the program initiated a mean dose of 1.7 days after onset of symptoms.
- When assessing symptoms by NEWS during the 14-day treatment period, it was found that the group receiving Favipiravir was 79% better, compared to 32.3% in the control group.
- The favipiravir group improved significantly faster. by half of the recipients Favipiravir showed improvement on day 2 of treatment compared to 14 days in the control group.
- The number of viruses in the patient Favipiravir was not significantly different from the control group until days 13 and 28 of treatment, where it was found that Favipiravir has a lower viral load.
- SIDE EFFECTS: A significant increase in uric acid levels was observed in patients treated with favipiravir compared to controls. No other different side effects were found.
Recommendations and conclusions
- If infected with COVID-19 Favipiravir should be taken as soon as the symptoms are mild, with a dosage of 1,800 mg morning-evening on the first day and 800 mg morning-evening the next day.
- Favipiravir in oral form is inexpensive and very safe. There are no side effects to worry about.
- The results of this study did not show efficacy in severely ill patients.
- Avoid using this medication in pregnant women. because it may harm an unborn baby especially the first quarter
Proofread by….Suree Silawong