How antibiotics work to fight infections

by time news

2023-09-28 09:41:29

Antibiotics have revolutionized modern medicine since their discovery in the 20th century. These powerful weapons against bacterial infections have saved countless lives. Let’s learn how antibiotics work to fight infections and why it is essential to use them responsibly.

The Invisible Enemy: Bacteria

Before we dive into the world of antibiotics, it’s important to understand who they are intended to combat: bacteria. These single-celled microorganisms can cause a wide variety of infections in humans, from respiratory infections to urinary tract infections and more.

The Mechanism of Action of Antibiotics

Antibiotics work in several ways to fight bacteria. Here are some of the most common mechanisms:

1. Cell Wall Inhibition: Some antibiotics, such as penicillin, interfere with the synthesis of the cell wall of bacteria. This weakens the structure of the bacteria and makes them more susceptible to destruction.

2. Inhibition of Protein Synthesis: Other antibiotics, such as aminoglycosides, block protein synthesis in bacteria. Without functional proteins, bacteria cannot perform their vital functions and die.

3. Inhibition of DNA Replication: Some antibiotics, such as quinolones, effectively prevent bacteria from duplicating their DNA. This disrupts the bacteria’s ability to reproduce.

4. Damage to Genetic Material: Other antibiotics, such as fluoroquinolones, cause direct damage to bacterial DNA, leading to cell death.

Selective Effects and Toxicity

An important characteristic of antibiotics is their ability to specifically attack bacteria without harming human cells. This is known as “selectivity.” However, some antibiotics can have side effects or cause toxicity if used incorrectly or excessively. That is why it is crucial to follow medical instructions and complete the entire course of treatment.

Antibiotic Resistance: A Growing Threat

Despite their effectiveness, antibiotics face a significant challenge: bacterial resistance. Bacteria can develop resistance to antibiotics over time, making the medications less effective. This resistance has become a global public health concern, and it is essential to use antibiotics responsibly and only under medical prescription.

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